Scientific Programme

6th of October

  • 9.00-9.10 Opening address – Tomasz Rzymkowski - Ministry of Education and Science,  Andrzej Kawecki (NRIO, Warsaw), Michał Mikula (NRIO, Warsaw).  
  • 9.10-9.40 Opening lecture –  Mien-Chie Hung (China Medical Univ.Taichung, Taiwan): Marker-guided target cancer therapy

Session: CAR-T as modern adopitve therapy
Chairs:  Zygmunt Pojda & Radosław Zagożdżon

  • 9.40-10.00 Radosław Zagożdżon (WUM Warsaw): PD-L1 molecule as a potential target for anticancer CAR-T immunotherapy
  • 10.00-10.20 Zygmunt Pojda (NRIO Warsaw): Decentralized versus centralized CAR-T production - pros and contras.
  • 10.20-10.40 Sébastien Walchli  (Oslo University Hospital, Oslo): Surprises and challenges in CAR development: the interesting case of CD37CAR
  • 10.40-11.00 Halvard Boening: Finding one's niche in the CAR arena.
  • 11.00-11.10 Coffee break

Session: Molecular diagnostics and markers in cancer, 
Chairs:  Andrzej Tysarowski & Janusz Siedlecki

Session patron AstraZeneca

  • 11.10-11.30 Andrzej Tysarowski (NRIO, Warsaw): Application of Molecular Biology Methods in Oncological Diagnostics
  • 11.30-11.50 Małgorzata Oczko-Wojciechowska (NRIO, Gliwice): The role of molecular tests in preoperative diagnostics of thyroid cancer.
  • 11.50-12.10 Beata Jagielska : (Prezes Polskiej Koalicji Medycyny Personalizowanej) What will be requirements around matching a specific diagnostic test with a specific therapy based on lung cancer     
  • 12.10-12.30  Andrzej Nowakowski (NRIO, Warsaw): The use of novel technologies in cervical cancer screening – the Polish perspective
  • 12.30-12.45 Monika Słowińska (NRIO, Warsaw): An In Vivo Visualization Of Cutaneous Squamous Cell Carcinoma Microenvironment Under Immunotherapy using Reflectance Confocal Microscopy.
  • 12.45-13.00 Coffee break

Session:  Molecular Biology and Cancer 
Chairs: Piotr Widłak & Ewa Grzybowska

  • 13.00-13.20 Wiesława Widłak (NRIO, Gliwice): How Heat Shock Factor 1 (HSF1) prevents inflammation under stress? 
  • 13.20-13.40 Dorota Ścieglińska (NRIO, Gliwice): The role of Heat Shock Protein A2 in the regulation of human epidermal homeostasis.
  • 13.40-14.00 Marek Rusin (NRIO, Gliwice): Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes.
  • 14.00-14.20 Anna Wojakowska (Institute of Bioorganic Chemistry, Poznań): Proteomic and metabolomic profiling of serum exosomes from cancer patients treated by ionizing radiation.
  • 14.20-14.40 Natalia Marek-Trzonkowska (University of Gdańsk): Immune response in non-small cell lung cancer and perspectives for immunotherapy.
  • 14.40-15.00 Lunch

Session: Chromatin and epigenetics
Chairs:  Tomasz Sarnowski & Richard Bayliss

  • 15.00-15.20 Tomasz Turowski (IBB PAS, Warsaw): Targeting RNA polymerase I – mechanistic link between transcription,r-loops and DNA instability.
  • 15.20-15.40 Richard Bayliss (Leeds University, UK): A moving target: in pursuit of Myc inhibitors
  • 15.40-15.50 Agnieszka Robaszkiewicz (UŁ, Łódź): The role of chromatin remodelling complex SWI/SNF in gaining cancer drug resistance during paclitaxel-based chemotherapy
  • 15.50-16.10 Gabriele Büchel (University Hospital Würzburg, Germany): Inducing transcription–replication conflicts as a therapy in neuroblastoma.
  • 16.10-16.40 Special guest  Jay Berzofsky (NCI, Bethesda, USA): Cancer vaccine studies from bench to bedside and back to the bench.
  • 16.40-17.10 Coffee break and poster session

Session: Recent advances in molecular biology of thyroid cancer
Chair: Damian Gaweł & Marlena Godlewska

  • 17.10-17.30 Marlena Godlewska (CMKP, Warsaw): Role of FERM family proteins in thyroid cancer.
  • 17.30-17.50 Małgorzata Grzanka: (CMKP, Warsaw): Role of extracellular vesicles in the progression of thyroid cancer.
  • 17.50-18.10 Maciej Ratajczak: (CMKP, Warsaw): Kinase-targeted therapies in thyroid cancer: progress and challenges.
  • 18.10-18.30 Dagmara Rusinek (NRIO, Gliwice): State of the art in the molecular prognostic factors in differentiated thyroid cancer.
  • 19.00 Dinner

7th of October

Session: Prostate cancer
Chair: Alfonso Urbanucci & Paweł Wiechno

  • 9.00-9.20 Mateusz Dąbkowski (NRIO, Warszawa): How irradiation of the primary affects course of dissease in metastatic prostate cancer patients.
  • 9.20-9.40  Alfonso Urbanucci  (Oslo University Hospital, Oslo): Single-cell analysis and spatial transcriptomics reveal insights into (prostate) cancer relapse.
  • 9.40-10.00  Pawel Wiechno (NRIO, Warsaw): Prostate cancer - is it always better to diagnose and treat earlier?
  • 10.00-10.30  Three the best abstracts will be selected for 10 min prsentation.
  • 10.30-10.40 Coffee break

Session:  Biology of head and neck cancer
Chairs:  Monika Pietrowska & Piotr Widłak

  • 10.40-11.00 Tomasz Rutkowski (NRIO, Gliwice): HPV related and not related oropharyngeal cancer. Patients characteristic and treatment results in material of NRIO Gliwice.
  • 11.00-11.20 Agnieszka Mazurek (NRIO, Gliwice): Circulating HPV16 DNA in the management of patients with oropharyngeal cancer - practical application.
  • 11.20-11.40 Beata Biesaga (NRIO, Kraków): New prognostic indicators in HPV‑positive oropharyngeal cancer. [on-line]
  • 11.40-11.55 Dirk Biskup (CeGaT GmbH, Tuebingen), Precision Diagnostics and Precision Medicine.
  • 11.55-12.15 Piotr Widłak (MUG, Gdańsk): Exosomes - mediators of signals released by head and neck cancer cells.
  • 12.15-12.35 Jadwiga Jabłońska (University Hospital, Essen): Neutrophil-mediated immunoregulation during head-and-neck cancer progression: new APCs on the block.
  • 12.35-12.55 Marta Gawin (NRIO, Gliwice): Mass Spectrometry Imaging of head and neck cancer.
  • 12.55 - 13.10 Coffee break

Short oral presentation

  • 13.10-13.40  six abstracts  will be selected by the Scientific Committee for the spotlight presentation  5 min. 
  • 13.40 -14.10 Lunch

NRIO internal grant session

Chair: Michał Mikula

  • 14.10-15.30  NRIO internal grant presentations
  • 15.30-16.00 Closing lecture Theresa Whiteside: (Pittsburgh University, USA): Tumor-derived exosomes and their role as potential biomarkers of cancer progression.
  • 16.00 Closing remarks